Aswini Panigrahi

Education

  • BVSc Orissa University of Science and Technology, Bhubaneswar, 1989     
  • DVM Indian Veterinary Research Institute, Izatnagar, 1993      
  • PhD All India Institute of Medical Sciences, New Delhi, 1998
  • Postdoctoral Studies at Seattle BioMed and University of Washington, Seattle, WA

Employment

  • Research Faculty, Georgetown University, Washington, DC

Previous Employment

  • Senior Scientist, Seattle BioMed, Seattle, WA (2002-2015)
  • Group Leader Proteomics Core Laboratory, KAUST, Jeddah (2010-2014)
  • Director Proteomics Core Laboratory, Children’s National, Washington, DC (2016-2021)

Background

I have a keen interest in developing and applying technologies in scientific research, and understanding biological processes and human diseases. During my PhD, I developed hepatitis C virus diagnostic assays, and carried out systematic studies on association of HCV with hepatitis, hepatocellular carcinoma (HCC), and sero-prevalence in blood donor population in India. During the postdoctoral period, I studied multi-protein complexes involved in mitochondrial RNA processing; identified and demonstrated the functions of protein components required for U-insertion-deletion RNA editing in lower eukaryotes. Continuing on my interest in mitochondrial biology, I performed deep proteome analyses, and created a comprehensive mitochondrial protein-protein interaction map using experimental and OMICS approach. I have developed and led institutional proteomics core laboratories; established high throughput pipeline for large scale proteomic data generation and analyses, comparative global proteome quantitation, and multi-protein complex analyses. At Children’s National, working with multi-disciplinary research teams, I developed and implemented neoantigen identification workflow in pediatric brain tumors, using high resolution mass spectrometry and personalized proteo-genomic techniques. Currently at GU, I am focused on head and neck cancer biomarker validation; and understanding the glyco-proteome in specific cancer cells, and multi-protein complexes.