New details on the function of N-glycans in the FcγRIIIa interaction with IgG

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A paper by Van Coillie et al. shows that afucosylated N-glycans of IgG have highest affinity for the oligomannose FcγRIIIa, a glycan structure commonly found on Asn162 on FcγRIIIa expressed by NK cells. doi:10.3389/fimmu.2022.987151.