Updated findings on the inhibition of SULF enzymes by a fucosylated GAG isolated from a sea cucumber.

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Farrag M, Aljuhani R, Benicky J, Al Ahmed H, Misra SK, Mishra SK, Sharp JS, Doerksen RJ, Goldman R, Pomin VH. Heparan-6-O-endosulfatase 2, a cancer-related proteoglycan enzyme, is effectively inhibited by a specific sea cucumber fucosylated glycosaminoglycan. Glycobiology. 2025 Apr 23;35(6). doi: 10.1093/ glycob/cwaf025. PMID: 340302034