Archive: News
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Updated findings on the inhibition of SULF enzymes by a fucosylated GAG isolated from a sea cucumber.
Farrag M, Aljuhani R, Benicky J, Al Ahmed H, Misra SK, Mishra SK, Sharp JS, Doerksen RJ, Goldman R, Pomin VH. Heparan-6-O-endosulfatase 2, a cancer-related proteoglycan enzyme, is effectively inhibit
Category: News
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Reem Aljuhani published our results on the production and inhibition of SULF1
Aljuhani R, Benicky J, Panigrahi A, Mukherjee P, Sanda M, Zhu S, Nováková Z, Pomin VH, Liu J, Davidson B, Bařinka C, Goldman R. Production and inhibition of human Heparan 6-O-Endosulfatase SULF1. Gly
Category: News
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SULF1 in endothelial senescence and atherosclerosis
Jiang MT, Wan SL, Shen XY, Zhang ZB, He ZQ, Hu YX, Liang C. SULF1's Role in Endothelial Senescence and Atherosclerosis: Insights from Single-Cell and Bulk Transcriptomics. J Inflamm Res. 2025 Dec 16;
Category: News
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SULF1 in reward and aversion learning
Miya K, Ohta K, Keino-Masu K, Okada T, Mizuno S, Takahashi S, Macpherson T, Hikida T, Masu M. Essential Roles of Heparan Sulfate Endosulfatase Sulf1 in Reward and Aversion Learning Through Distinct D
Category: News
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SULF2 inhibition sensitizes TNBC to paclitaxel
Manouchehri JM, Datta J, Marcho LM, Stover D, Ganju RK, Ramaswamy B, Carson WE, Mittra A, Zhang X, Schnell PM, Yue Y, Rubinstein MP, Cherian MA. Sulfatase 2 inhibition sensitizes triple-negative brea
Category: News
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Our study of SARS-CoV-2 glycosylation reached 226 citations
Sanda M, Morrison L, Goldman R. (2021) N- and O-glycosylation of the SARS-CoV-2 spike protein. Anal Chem. 2021 Feb 2;93(4):2003-2009. PMID: 33406838
Category: News
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Aspirin reduces SARS-CoV-2 binding to ACE2 via altered glycosylation of the spike protein
Perico L, Bovio A, Tomasoni S, Trionfini P, Cerullo D, Corna D, Pezzotta A, Locatelli M, Alberti M, Benigni A, Remuzzi G. Acetylsalicylic acid disrupts SARS-CoV-2 spike protein glycosylation and sele
Category: News
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SULF1 promotes colon cancer metastasis and treatment resistance
Li H, Xie Y. MARCHF1-mediated SULF1 degradation blocks THBS2/TGF-β/SMAD2/3 signaling to reverse colon cancer metastasis and 5-FU resistance. iScience Volume 29, Issue 1114476 January 16, 2026
Category: News
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Real-time proteomics in oncology tumor boards
Hunt AL, Randall J, Mansukhani MM, Nyberg K, Nutcharoen A, Davis J, Corgiat B, Mueller C, Melvin S, Sharma M, Johnston L, Swain W, Abulez T, Bateman NW, Maxwell GL, Deeken J, Benyounes A, Petricoin E
Category: News
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Histology-resolved proteomics in prostate cancer
Hunt AL, Barakat W, Makohon-Moore SC, Hood BL, Conrads KA, Wilson KN, Abulez T, Ogata J, Pienta KJ, Lotan TL, Mani H, Trump DL, Bateman NW, Conrads TP. Histology-resolved proteomics reveals distinct
Category: News