Archive: News
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Collagen organization regulates tumor progression
A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy. Di Martino JS, Nobre AR, Mondal C, Taha I, Farias EF, Fertig EJ, Naba A, Aguirre-Ghiso JA, Bravo-Cordero JJ. Nat Cancer
Category: News
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Collagen regulates tumors by immunosuppression
Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. Sun X, Wu B, Chiang HC, Deng H, Zhang X, Xiong W, Liu J, Rozeboom AM, Harris BT, Blommaert E, Gomez A, Garcia RE, Zhou Y,
Category: News
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Dr. Panigrahi co-authors a Nature Communications proteogenomic study of neoantigens
Proteogenomic discovery of neoantigens facilitates personalized multi-antigen targeted T cell immunotherapy for brain tumors. Rivero-Hinojosa S, Grant M, Panigrahi A, Zhang H, Caisova V, Bollard CM,
Category: News
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More evidence that glycosylkation affects SARS-CoV-2 infectivity
SARS-Cov-2 Spike binding to ACE2 is stronger and longer ranged due to glycan interaction. Huang Y, Harris BS, Minami SA, Jung S, Shah PS, Nandi S, McDonald KA, Faller R Biophysical Journal (2022) doi
Category: News
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Non-redundant function of 6-O-endosulfatases in the developing spinal cord
Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord. Danesin C, Darche-Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, Ohayon D, Glise B, Soula C Sci Re
Category: News
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Inhibition of 6-O-endosulfatases accelerates oligodendrocyte recruitment and remyelination
Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination. Saraswat D, Shayya HJ, Polanco JJ, Tripathi A, Welliver RR, Pol SU, Seidm
Category: News
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O-glycosylation regulates furin cleavage of the SARS-CoV-2 spike
Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation. Zhang L, Mann M, Syed ZA, Reynolds HM, Tian E, Samara NL, Zeldin DC, Tabak LA, Ten Hagen KG. Proc Natl Acad Sci U S A. 2021 Nov
Category: News
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Targeting evolutionarily-conserved N-glycosylation affects SARS-CoV-2 infectivity
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro. Hsiang-Chi Huang, Yun-Ju Lai, Chun-Che Liao, Wang-Feng Yang, Ke-Bin Huang, I-Jung Lee, Wen-Cheng Chou, Shih-Han Wang,
Category: News
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Dr Edwards presents on GNOme ontology at ICBO 2021
“GNOme – Glycan Naming and Subsumption Ontology" Wenjin Zhang and Nathan Edwards at the 12th International Conference on Biomedical Ontologies (2021).
Category: News
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Dr Sanda presents November 2nd on the quantification of IgG glycoforms at the 69th ASMS Conference
“Inter- and intra-scan normalization for optimized LC-MS-PRM workflow of IgG glycosylation measurement.” Miloslav Sanda, Qiang Yang, Lai-xi Wang, Radoslav Goldman This collaborative study highligh
Category: News