An elegant method for selective de-glycosylation of O-GlcNAcylated proteins in cells with application to transcriptional regulation of c-Jun and c-Fos

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Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase. Ge Y, Ramirez DH, Yang B, D’Souza AK, Aonbangkhen C, Wong S, Woo CM. Nat Chem Biol. 2021 Mar 8. doi: 10.1038/s41589-021-00757-y. Online ahead of print. PMID: 33686291