Researchers confirm that human SULF2 is a cancer-promoting chondroitin sulfate proteoglycan

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Extracellular endosulfatase Sulf-2 harbors a chondroitin/dermatan sulfate chain that modulates its enzyme activity. El Masri R, Seffouh A, Roelants C, Seffouh I, Gout E, Pérard J, Dalonneau F, Nishitsuji K, Noborn F, Nikpour M, Larson G, Crétinon Y, Friedel-Arboleas M, Uchimura K, Daniel R, Lortat-Jacob H, Filhol O, Vivès RR. Cell Rep. 2022 Mar 15;38(11):110516 https://doi.org/10.1016/j.celrep.2022.110516