Sialic acid on ACE2 and heparan sulfation modify SARS-CoV-2 infectivity

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Host and viral determinants for efficient SARS-CoV-2 infection of the human lung. Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, Shuai H, Yang D, Hou Y, Zhang X, Yuen TT, Cai JP, Zhang AJ, Zhou J, Yuan S, To KK, Chan IH, Sit KY, Foo DC, Wong IY, Ng AT, Cheung TT, Law SY, Au WK, Brindley MA, Chen Z, Kok KH, Chan JF, Yuen KY. Nat Commun. 2021 Jan 8;12(1):134. PMID: 33420022 doi: 10.1038/s41467-020-20457-w.