Archive: News
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Non-redundant function of 6-O-endosulfatases in the developing spinal cord
Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord. Danesin C, Darche-Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, Ohayon D, Glise B, Soula C Sci Re
Category: News
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Inhibition of 6-O-endosulfatases accelerates oligodendrocyte recruitment and remyelination
Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination. Saraswat D, Shayya HJ, Polanco JJ, Tripathi A, Welliver RR, Pol SU, Seidm
Category: News
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O-glycosylation regulates furin cleavage of the SARS-CoV-2 spike
Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation. Zhang L, Mann M, Syed ZA, Reynolds HM, Tian E, Samara NL, Zeldin DC, Tabak LA, Ten Hagen KG. Proc Natl Acad Sci U S A. 2021 Nov
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Targeting evolutionarily-conserved N-glycosylation affects SARS-CoV-2 infectivity
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro. Hsiang-Chi Huang, Yun-Ju Lai, Chun-Che Liao, Wang-Feng Yang, Ke-Bin Huang, I-Jung Lee, Wen-Cheng Chou, Shih-Han Wang,
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Dr Edwards presents on GNOme ontology at ICBO 2021
“GNOme – Glycan Naming and Subsumption Ontology" Wenjin Zhang and Nathan Edwards at the 12th International Conference on Biomedical Ontologies (2021).
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Dr Sanda presents November 2nd on the quantification of IgG glycoforms at the 69th ASMS Conference
“Inter- and intra-scan normalization for optimized LC-MS-PRM workflow of IgG glycosylation measurement.” Miloslav Sanda, Qiang Yang, Lai-xi Wang, Radoslav Goldman This collaborative study highligh
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CTGRC researchers publish a collaborative study of PSMA glycoforms
"Glycoforms of human Prostate-specific membrane antigen (PSMA) in human cells and prostate tissue" Wei Yuan, Baoqin Liu, Miloslav Sanda, Renhuizi Wei, Julius Benicky, Zora Novakova, Cyril Barinka, Ra
Category: News
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A study of glycoproteomics tools is accepted in Nature Methods
“Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies of Serum N- and O-Glycopeptide Data”, Rebeca Kawahara, Anastasia Chernykh, Kathirvel Alagesan
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Dr. Aswini Panigrahi joins CTGRC
Dr. Panigrahi joins the analytical group to conduct mass spectrometric studies of glycoconjugates.
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CTGRC receives funds to install timsToF Pro mass spectrometer
NIH awards S10OD028623 to CTGRC researchers to study ion-mobility assisted LC-MS/MS workflows for the quantification of glycopeptides, as well as structural resolution of glycoforms, using the timsTo
Category: News