Archive: News
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Our collaborative paper with Glycan Therapeutics on MS analysis of SULF activity is a Glycobiology Editor’s Choice
Development of a method to measure the activity of heparan sulfate 6-endosulfatase for biological research. Wang Z, Benicky J, Mukherjee P, Laing J, Xu Y, Pagadala V, Wu S, Hippensteel JA, Goldman R,
Category: News
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Our collaboration with colleagues at the University of Mississippi reveals how glycan polymers inhibit Sulf-2 activity
Galectin-3-binding protein inhibits extracellular heparan 6-O-endosulfatse Sulf-2. Panigrahi A, Benicky J, Aljuhani R, Mukherjee P, Nováková Z, Bařinka C, Goldman R. bioRxiv. 2023 Dec 21:2023.12.20.5
Category: News
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Congrats to Dr. Panigrahi & colleagues on a spatially resolved proteomics study of FFPE tissues of HNSCC patients
dia-PASEF Proteomics of Tumor and Stroma LMD Enriched from Archived HNSCC Samples. Panigrahi A, Hunt AL, Assis D, Willetts M, Kallakury BV, Davidson B, Ahn J, Conrads TP, Goldman R. ACS Omega. 2025 M
Category: News
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SULFs in cancer metastasis
6-O-endosulfatases in tumor metastasis: heparan sulfate proteoglycans modification and potential therapeutic targets. Han M, Zhu H, Chen X, Luo X. Am J Cancer Res. 2024 Feb 25;14(2):897-916. doi: 10.
Category: News
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Glycoproteins and cancer-stromal cell interactions mediate resistance to HER2-targeting therapies
Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies. Goyette MA, Stevens LE, DePinho CR, Seehawer M, Nishida J, Li Z,
Category: News
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Mucin-selective proteolytic degradation
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins. Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malak
Category: News
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A review of glycosaminoglycan biology
A biological guide to glycosaminoglycans: current perspectives and pending questions. Ricard-Blum S, Vivès RR, Schaefer L, Götte M, Merline R, Passi A, Heldin P, Magalhães A, Reis CA, Skandalis SS, K
Category: News
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Congrats to Dr. Pritha Mukherjee on a paper on inhibitors of HNSCC cell invasion
Aspartate β-Hydroxylase Is Upregulated in Head and Neck Squamous Cell Carcinoma and Regulates Invasiveness in Cancer Cell Models. Mukherjee P, Zhou X, Galli S, Davidson B, Zhang L, Ahn J, Aljuhani R,
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Congrats to Amy Lum
Congrats to Amy Lum, undergraduate student researcher, on receipt of a Laidlaw scholarship supporting her research at the CTGRC.
Category: News
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A novel way to model protein-carbohydrate interactions
Highly accurate carbohydrate-binding site prediction with DeepGlycanSite. Xinheng He, Lifen Zhao, Yinping Tian, Rui Li, Qinyu Chu, Zhiyong Gu, Mingyue Zheng, Yusong Wang, Shaoning Li, Hualiang Jiang,
Category: News