Archive:News
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Our study of SARS-CoV-2 glycosylation reached 226 citations
Sanda M, Morrison L, Goldman R. (2021) N- and O-glycosylation of the SARS-CoV-2 spike protein. Anal Chem. 2021 Feb 2;93(4):2003-2009. PMID: 33406838
Category: News
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Aspirin reduces SARS-CoV-2 binding to ACE2 via altered glycosylation of the spike protein
Perico L, Bovio A, Tomasoni S, Trionfini P, Cerullo D, Corna D, Pezzotta A, Locatelli M, Alberti M, Benigni A, Remuzzi G. Acetylsalicylic acid disrupts SARS-CoV-2 spike protein glycosylation and sele
Category: News
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SULF1 promotes colon cancer metastasis and treatment resistance
Li H, Xie Y. MARCHF1-mediated SULF1 degradation blocks THBS2/TGF-β/SMAD2/3 signaling to reverse colon cancer metastasis and 5-FU resistance. iScience Volume 29, Issue 1114476 January 16, 2026
Category: News
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Real-time proteomics in oncology tumor boards
Hunt AL, Randall J, Mansukhani MM, Nyberg K, Nutcharoen A, Davis J, Corgiat B, Mueller C, Melvin S, Sharma M, Johnston L, Swain W, Abulez T, Bateman NW, Maxwell GL, Deeken J, Benyounes A, Petricoin E
Category: News
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Histology-resolved proteomics in prostate cancer
Hunt AL, Barakat W, Makohon-Moore SC, Hood BL, Conrads KA, Wilson KN, Abulez T, Ogata J, Pienta KJ, Lotan TL, Mani H, Trump DL, Bateman NW, Conrads TP. Histology-resolved proteomics reveals distinct
Category: News
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Our review of heparan sulfatase mechanism of action and inhibition
Mayieka M, Benicky J, Goldman R, Huang X. Sulfatases: Catalytic Mechanism, Substrate Preferences, and Carbohydrate-Based Inhibitor Design. Israel Journal of Chemistry. 2025 Dec 20. doi: 10.1002/ijch.
Category: News
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Gregory Furletti will present our study of SULF1 in HNSCC at the USCAP in San Antonio
Furletti G, Llaguno Guerrero TJ, Schrom EC, Goldman R, Davidson B, Kallakury B. Spatial Patterning Analysis of SULF1 Expression at Tumor–Stroma Interfaces in Head and Neck Squamous Cell Carcinoma: A
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Congrats to Pritha on a SULF1 paper accepted in Cancer Medicine
Mukherjee P, Benicky J, Panigrahi A, Ailles L, Goldman R. SULF1 in cancer associated fibroblasts promotes invasion in head and neck cancer cell lines. Cancer Medicine, in press
Category: News
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Reem Aljuhani presents a poster on SULF1 structure-activity at the NIH-FDA Glycoscience Research Day
Aljuhani, R., Benicky, J., Panigrahi, A., Mukherjee, P., Nováková, Z., Bařinka, C., Liu, J., Goldman, R. Purification and in vitro Characterization of Human Extracellular Heparan 6-O-endosulfatases S
Category: News
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Dr. Panigrahi shows that Galectin-3-Binding Proptein is a specific and selective inhibitor of Sulf-2
Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2. Panigrahi A, Benicky J, Aljuhani R, Mukherjee P, Nováková Z, Bařinka C, Goldman R. Mol Cell Proteomics. 2024 Jul;23
Category: News