Archive: News
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CTGRC Announces Glycopeptide DIA Interlaboratory Study
Dr. Miloslav Sanda, Director of Analytical Chemistry at the CTGRC, announced the Glycopeptide DIA Interlaboratory Study today. Please contact Mila (ms2465@goergetown.edu) if you are interested in par
Category: News
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Sialic acid, in addition to heparan sulfate, mediates viral entry of SARS-CoV-2
Sialic Acid-Dependent Binding and Viral Entry of SARS-CoV-2. Linh Nguyen, Kelli A. McCord, Duong T. Bui, Kim M. Bouwman, Elena N. Kitova, Dhanraj Kumawat, Gour C. Daskhan, Ilhan Tomris, Ling Han, Pra
Category: News
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Glycans in SARS-CoV-2 antibody production
Glycans of SARS-CoV-2 Spike Protein in Virus Infection and Antibody Production. Xiaohui Zhao, Huan Chen, Hongliang Wang. Front Mol Biosci 2021 Apr 13;8:629873. eCollection 2021. doi: 10.3389/fmolb.2
Category: News
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CTGRC Virtual Posters at the 2021 NIH & FDA Glycoscience Research Day on June 1st
Conference website and registration. “Disialo T antigen in the progression of liver disease”, Miloslav Sanda, Julius Benicky, and Radoslav Goldman. “Purification and characterization of human r
Category: News
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Therapeutic implications of the inhibition of SULF2
SULF2 monoclonal antibody 5D5 suppresses human cholangiocarcinoma xenograft growth via regulation of a SULF2-PDGFRβ-YAP signaling axis. Luo X, Campbell NA, He L, O'Brien DR, Singer MS, Lemjabbar-Alao
Category: News
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Mucin domain-targeting proteases open new avenues in mucin research
Classification, structural biology, and applications of mucin domain-targeting proteases. Shon DJ, Kuo A, Ferracane MJ, Malaker SA. Biochem J. 2021 Apr 30;478(8):1585-1603. doi: 10.1042/BCJ20200607
Category: News
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A nice study of SARS-CoV-2 binding to heparan sulfate
Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3-O-sulfated heparan sulfate. Vaibhav Tiwari, Ritesh Tandon, Nehru Viji Sankaranarayanan, Jacob C. Beer, Ellen K. K
Category: News
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Advances in the studies of SARS-CoV-2 O-glycosylation
Altered O-glycosylation Level of SARS-CoV-2 Spike Protein by Host O-glycosyltransferase Strengthens Its Trimeric Structure. Zhijue Xu, Xin Ku, Jiaqi Tian, Han Zhang, Jingli Hou, Can Zhang, Jingjing S
Category: News
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A nice summary of Glycosaminoglycan–Protein Interactions
Glycosaminoglycan-Protein Interactions: The First Draft of the Glycosaminoglycan Interactome. Vallet SD, Clerc O, Ricard-Blum S. J Histochem Cytochem. 2021 Feb;69(2):93-104. doi: 10.1369/002215542094
Category: News
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A nice development in SULF-2 research: it is a proteoglycan
“Extracellular endosulfatase Sulf-2 harbours a chondroitin/dermatan sulfate chain that modulates its enzyme activity” Rana El Masri, Amal Seffouh, Caroline Roelants, Ilham Seffouh, Evelyne Gout, Juli
Category: News