Archive: News
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A paper on the glycopeptides of SARS CoV-2 displayed by MHCII to be published soon in Cell Reports
Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells. Parker R, Partridge T, Wormald C, Kawahara R, Stalls V, Aggelakopoulou M, Parker J, Doherty R
Category: News
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Sialic acid on ACE2 and heparan sulfation modify SARS-CoV-2 infectivity
Host and viral determinants for efficient SARS-CoV-2 infection of the human lung. Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, Shuai H, Yang D, Hou Y, Zhang X, Yuen TT, Cai JP, Zhang AJ, Zhou J, Yua
Category: News
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Dr. Sanda collaborates with SCIEX researchers on CESI TripleTOF LC-MS/MS analysis of Adalimumab glycoforms
The results were published in a Sciex release (https://sciex.com/content/dam/SCIEX/pdf/tech-notes/all/CESI_mAb.pdf) and presented by Mila at the US HUPO 2021 conference, virtual, 03/08/2021: “Site-sp
Category: News
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An elegant method for selective de-glycosylation of O-GlcNAcylated proteins in cells with application to transcriptional regulation of c-Jun and c-Fos
Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase. Ge Y, Ramirez DH, Yang B, D'Souza AK, Aonbangkhen C, Wong S, Woo CM. Nat Chem Biol. 2021 Mar 8. doi: 10.1038/s415
Category: News
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CTGRC researchers participate in an inter-laboratory glycoproteomics study in review at Nature Methods
"Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies of Glycopeptide Data." Rebeca Kawahara, Kathirvel Alagesan, Marshall Bern, Weiqian Cao, Rober
Category: News
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A new report on lysosomal exit of SARS CoV-2 from infected cells
"β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway" Sourish Ghosh, Teegan A Dellibovi-Ragheb, Adeline Kerviel, Eowyn Pak, Qi Qiu, Matthew Fisher, Peter M Takvoria
Category: News
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An update on the S1 glycoforms of the SARS-CoV-2 released by CALU-3 cells
"Analysis of SARS-CoV-2 spike glycosylation reveals shedding of a vaccine candidate." Juliane Brun, Snežana Vasiljevic, Bevin Gangadharan, Mario Hensen, Anu V. Chandran, Michelle L. Hill, J.L. Kiappe
Category: News
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Yang Yang has a new publication on heparan sulfation in Frontiers in Oncology
Yang's paper "Expression of the Extracellular Sulfatase SULF2 Affects Survival of Head and neck Squamous Cell Carcinoma Patients" was just accepted at https://www.frontiersin.org/articles/10.3389/fon
Category: News
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Dr. Miloslav Sanda (CTGRC Director of Analytical Chemistry) will present at Stanford
Mila presents on “Structure and Site-specific N- and O- Glycosylation of the SARS-CoV-2 Spike Glycoprotein using Low Collision Energy Fragmentation and Cyclic Ion Mobility” at the upcoming Stanford R
Category: News
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Dr. Sanda describes SARS CoV2 glycoforms
Mila's paper "N and O glycosylation of the SARS-CoV-2 spike protein" is in bioRxiv at https://doi.org/10.1101/2020.07.05.187344
Category: News